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Publikationen

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Publikationen / Publications


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2022



N. Tajuddeen, D. Feineis, H. Ihmels, G. Bringmann,  Acc. Chem. Res. 2022
The Stereoselective Total Synthesis of Axially Chiral Naphthylisoquinoline Alkaloids
https://doi.org/10.1021/acs.accounts.2c00432

R. Schulte, H. Ihmels, Beilstein J. Org. Chem 2022, 18, 368-373.
Borylated norbornadiene derivatives: Synthesis and application in Pd-catalyzed Suzuki-Miyaura coupling reactions
Open access: https://www.beilstein-journals.org/s/ZHyvPB69Yt

P. Groß, H. Ihmels, J. Org. Chem. 2022, 87, 4010−4017. https://doi.org/10.1021/acs.joc.1c02755
Synthesis of fluorescent, DNA-binding benzo[b]indolonaphthyridinium derivatives by a misguided Westphal condensation

J. Schlosser, H. Ihmels,Curr. Org. Synth. 2022, in press.
Ligands for abasic site-containing DNA and their use as fluorescent probes

P. J. Wickhorst, H. Ihmels, M. Marianne Lammert-Baumgartner, M. Müller, H. Schönherr, New J. Chem. 2022, 46, 39–43 
9-Nitrobenzo[b]quinolizinium as Fluorogenic Probe for the Detection of Nitroreductase in vitro and in Escherichia coli
Open access: pubs.rsc.org/en/content/articlepdf/2021/NJ/D1NJ05230F



2021

P. J. Wickhorst, H. Ihmels, T. Paululat, Molecules 2021, 26, 6595.
Studies on the interactions of 3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium and insulin with the quadruplex-forming oligonucleotide sequence a2 from the insulin-linked polymorphic region

P. J. Wickhorst, S. I. Druzhinin, H. Ihmels, M. Müller, M. S. Sardo, H. Schönherr, G. Viola, ChemPhotoChem, 2021, 5, 1079–1088. 
A dimethylaminophenyl-substituted naphtho[1,2-b]quinolizinium as multicolor NIR probe for the fluorimetric detection of intracellular nucleic acids and proteins

P. J. Wickhorst, H. Ihmels, Chem. Eur. J. 2021, 27, 8580–8589
Selective, pH-Dependent Colorimetric and Fluorimetric Detection of Quadruplex DNA with 4-Dimethylamino(phenyl)-Substituted Berberine Derivatives

P. J. Wickhorst, M. Blachnik, D. Lagumdzija, H. Ihmels, Beilstein J. Org. Chem. 2021,17, 991–1000.
Synthesis of 10-O-Aryl-Substituted Berberine Derivatives by Chan-Evans-Lam Coupling and Investigation of their DNA-Binding Properties

P. J. Wickhorst, H. Ihmels, Molecules 2021, 26, 2566.
Berberrubine phosphate: A selective Fluorescent Probe for Quadruplex DNA

W. Fudickar, M. Bauch, H. Ihmels, T. Linker, Chem. Eur. J. 2021, 27, 13591–1604.  
DNA-Triggered Enhancement of Singlet Oxygen Production by Pyridinium Alkynylanthracens
Open access: https://doi.org/10.1002/chem.202101918

R. Bortolozzi, H. Ihmels, R. Schulte, C. Stremmel, G. Viola, Org. Biomol. Chem. 2021, 19, 878–890.
Synthesis, DNA-binding and antiproliferative properties of diarylquinolizinium derivatives
Open access: https://pubs.rsc.org/en/Content/ArticleLanding/2021/OB/D0OB02298E#!divAbstract

G. E. Gomez Pinheiro, H. Ihmels, J. Fluoresc. 2021, 31, 269–277.
Fluorimetric detection of Zn2+, Mg2+, and Fe2+ with 3-hydroxy-4-pyridylisoquinoline as fluorescent probe
Open access: https://link.springer.com/article/10.1007/s10895-020-02666-0



2020

J. Becher, D. V. Berdnikova, H. Ihmels, C. Stremmel, Beilstein J. Org. Chem. 2020, 16, 2795–2806.
Synthesis and investigation of quadruplex-DNA-binding, 9-O-substituted berberine derivatives
Open access:
https://doi.org/10.3762/bjoc.16.230

P. M. Pithan, K. Schwan, H. Ihmels, Arkivoc 2020, vii, 1–11.
Synthesis of fluorosolvatochromic phenanthrenyl-substituted benzoquinolizinium derivatives
Open access: https://doi.org/10.24820/ark.5550190.p011.298

P. M. Pithan, S. Steup, H. Ihmels, Beilstein J. Org. Chem. 2020, 16, 904–916.
Reversible photoswitching of the DNA-binding properties of styrylquinolizinium derivatives through photochromic [2+2] cycloaddition and cycloreversion
Open access: https://www.beilstein-journals.org/bjoc/articles/16/82

D. V. Berdnikova, Josef Heider, Heiko Ihmels, N. Sewald, P. M. Pithan, ChemPhotoChem. 2020, 4, 520–525.
Photoinduced release of DNA-binding ligands from the [4+4] dimers of benzo[b]quinolizinium and anthracene derivatives
Open access: https://doi.org/10.1002/cptc.202000015

S. Kölsch, H. Ihmels, J. Mattay, N. Sewald, B. O. Patrick, Beilstein J. Org. Chem. 2020, 16, 111-124.
Reversible photoswitching of the DNA-binding properties of styrylquinolizinium derivatives through photochromic [2+2] cycloaddition and cycloreversion
Open access: https://www.beilstein-journals.org/bjoc/articles/16/13

S. Müller, J. Paulus, J. Mattay, H. Ihmels, V. I. Dodero, N. Sewald, Beilstein J. Org. Chem. 2020, 16, 60–70.
Photocontrolled DNA minor groove interactions of Im/Py polyamides
Open access: https://www.beilstein-journals.org/s/EEU7EhbidO

P. M. Pithan, H. Ihmels, J. Heterocycl. Chem. Chem. 2020, 57, 1435–1441.
Studies on the photocyclization reaction of 8-styryl-substituted coralyne derivatives
Open access: https://onlinelibrary.wiley.com/doi/10.1002/jhet.3858

J. Schlosser, R. Cibulka, P. Groß, H. Ihmels, C. J. Mohrschladt, ChemPhotoChem 2020, 4, 132–137.
Visible-light induced di-π-methane rearrangement of dibenzobarrelene derivatives
Open access: https://onlinelibrary.wiley.com/doi/abs/10.1002/cptc.201900221



2019

P. M. Pithan, C. Kuhlmann, C. Engelhard, H. Ihmels, Chem. Eur. J. 2019, 25, 16088-16098.
Synthesis of 5-alkyl- and 5-phenylamino-substituted azothiazole dyes with solvatochromic and DNA-binding properties
Open access: https://onlinelibrary.wiley.com/doi/10.1002/chem.201903657

C. Dohmen, H. Ihmels, R. Kreienmeier, B. O. Patrick, Chem. Comm. 2019, 55, 11071–11074.
Synthesis of a crystallochromic indolizine dye by a base- and catalyst-free photochemical route
Open access: https://pubs.rsc.org/en/content/articlelanding/2019/cc/c9cc04730a#!divAbstract

A. K. Das, S. I. Druzhinin, H. Ihmels, M. Müller, H. Schönherr, Chem. Eur. J. 2019, 25, 12703–12707.
Colorimetric and fluorimetric DNA detection with a hydroxystyryl-quinolizinium photoacid and its application for cell imaging
Open access: https://onlinelibrary.wiley.com/doi/10.1002/chem.201903017

H. Ihmels, M. Karbasiyoun, K. Löhl, C. Stremmel Org. Biomol. Chem. 2019, 17, 6404-6413.
Structural flexibility versus rigidity of the aromatic unit of DNA ligands: Binding of aza- and azoniastilbene derivatives to duplex and quadruplex DNA
Open access: https://pubs.rsc.org/en/content/articlelanding/2019/ob/c9ob00809h#!divAbstract

A. Kumar Das, H. Ihmels, S. Kölsch, Photochem. Photobiol. Sci. 2019, 18, 1373-1381.
Diphenylaminostyryl-substituted quinolizinium derivatives are fluorescent light-up probes for duplex and quadruplex DNA
Open access: https://pubs.rsc.org/en/content/articlelanding/2019/pp/c9pp00096h#!divAbstract

G. E. Gomez Pinheiro, H. Ihmels, C. Dohmen, J. Org. Chem. 2019, 84, 3011–3016.
Mild Synthesis of Fluorosolvatochromic and Acidochromic 3-Hydroxy-4-pyridylisoquinoline Derivatives from Easily Available Substrates


2018

H. Ihmels, S. Jiang, M. M. A. Mahmoud, H. Schönherr, D. Wesner, I. Zamrik, Langmuir 2018, 34, 11866–11877.
Fluorimetric detection of G-quadruplex DNA in solution and adsorbed on surfaces with a selective trinuclear cyanine dye

H. Ihmels, K. Löhl, T. Paululat, S. Uebach, New J. Chem. 2018, 42, 13813–13818.
NMR-spectroscopic investigation of the complex between tetraazonia­pentapheno[6,7-h]pentaphene and quadruplex DNA Tel26

S.S. Murthy Bandaru, D. Dzubiel, H. Ihmels, M. Karbasiyoun, M. M. A. Mahmoud, C. Schulzke, Beilstein J. Org. Chem. 2018, 14, 1871–1884.
Synthesis of 9-arylalkynyl- and 9-aryl-substituted benzo[b]quinolizinium derivatives by Palladium-mediated cross coupling reactions by Palladium-mediated cross coupling reactions
Open access: https://www.beilstein-journals.org/bjoc/content/pdf/1860-5397-14-161.pdf?m=y

E. Yalçın, H. Duyar, H. Ihmels, Z. Seferoğlu, Spectrochim. Acta Part A 2018, 196, 423–438.
Spectroscopic studies of the interactions of 3,8-bis(alkylamido)-5-ethyl-6-phenyl-5-phenanthridinium bromide derivatives with quadruplex DNA

D. V. Berdnikova, N. I. Sosnin, O. A. Fedorova, H. Ihmels, Org. Biomol. Chem. 2018, 16, 545–554.
Governing the DNA-binding mode of styryl dyes by the length of their alkyl substituents – from intercalation to major groove binding


2017

B. E. Aney, H. Ihmels, R. C. White, Int. J. Org. Chem. 2017, 7, 263–268.
Photochemistry of Styrene Oxide: A Triplet Pathway in the Singlet Excitation of a Monoaryl Oxirane

H. Ihmels, M. M. A. Mahmoud, B. O. Patrick, J. Phys. Org. Chem. 2017, 30, e3736.
Optical differentiation between quadruplex DNA and duplex DNA with a [2.2.2]heptamethinecyanine dye

K. Schäfer, H. Ihmels, J. Fluoresc. 2017, 27, 1221–1224.
Ratiometric detection of water in acetonitrile with 9-hydroxybenzo[b]quinolizinium as fluorosolvatochromic probe

P. M. Pithan, D. Decker, S. I. Druzhinin, H. Ihmels, H. Schönherr, Y. Voß, RSC Advances, 2017, 7, 10660–10667.
8-Styryl-substituted coralyne derivatives as DNA binding fluorescent probes
Open access: http://pubs.rsc.org/en/content/articlehtml/2017/RA/C6RA27684

J. Becher, D. V. Berdnikova, D. Dzubiel, H. Ihmels, P. M. Pithan, Beilstein J. Org. Chem. 2017, 13, 203–212.
Interactions between photoacidic 3-hydroxy[1,2-b]naphthoquinolizinium and cucurbit[7]uril: Influence on acidity in the ground and excited state
Open access: http://www.beilstein-journals.org/bjoc/content/pdf/1860-5397-13-23.pdf

K. Schäfer, H. Ihmels, E. Porcù, G. Viola, Chem. Eur. J. 2017, 23, 370–379.
Control of the DNA-Binding and Antiproliferative Properties of Hydroxybenzo[b]quinolizinium Derivatives with pH and light


2016

A. E. Jortzik, K. Zocher, A. Isernhagen, B. M. Mailu, S. Rahlfs, G. Viola, S. Wittlin, N. H. Hunt, H. Ihmels, K. Becker, Antimicrob. Agents Chemother. 2016, 60, 115–125.
Benzo[b]quinolizinium derivatives have a strong antimalarial activity and inhibit indoleamine dioxygenase.

Z. Seferoğlu, M. M. A. Mahmoud, H. Ihmels, Dyes Pigm. 2016, 125, 241–248.
Studies of the binding interactions of dicationic styrylimidazo[1,2-a]pyridinium dyes with duplex and quadruplex DNA

A. Bergen, S. Rudiuk, M. Morel, T. Le Saux, H. Ihmels, D. Baigl, ACS Nanolett. 2016, 16, 773–780.
Photodependent Melting of Unmodified DNA Using a Photosensitive Intercalator: A New and Generic Tool for Photoreversible Assembly of DNA Nanostructures at Constant Temperature

A. K. Ernst, M. Liebscher, S. Mathea, A. Granzhan, J. Schmid, M. R. Popoff, H. Ihmels, H. Barth, C. Schiene-Fischer, Sci. Rep. 2016, 6, 20301.
A novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxin

A. Granzhan, H. Ihmels, Synlett 2016, 27, 1775–1793.
Playing around with size and shape of quinolizinium derivatives: Versatile ligands for duplex, triplex, quadruplex and abasic site-containing DNA

P. M. Pithan, D. Decker, M. Sutero Sardo, G. Viola, H. Ihmels, Beilstein J. Org. Chem. 2016, 12, 854–862.
Synthesis and Fluorosolvatochromism of 3-Arylnaphtho[1,2-b]quinolizinium derivatives

T. M. Aliyeu, D. V. Berdnikova, O. A. Fedorova, E. N. Gulakova, C. Stremmel, H. Ihmels, J. Org. Chem. 2016, 81, 9075–9085.
Regiospecific photocyclization of mono- and bis-styryl substituted N-heterocycles: A synthesis of DNA-binding benzo[c]quinolizinium derivatives

R. C. White, B. E. Arney Jr., J. Perry, N. Thompson, P. M. Pithan, S. von Gradowski, H. Ihmels, J. Heterocycl. Chem. 2016, 54, 1656–1659.
Ionic Pathways in the Photochemistry of Cyclic Sulfite Esters

K. Schäfer, H. Ihmels, C. Bohne, K. P. Valente, A. Granzhan, J. Org. Chem. 2016, 81, 10942–10954.
Hydroxybenzo[b]quinolizinium Ions: Water-Soluble and Solvatochromic Photoacids


2015

A. Granzhan, H. Ihmels, M. Tian, Arkivoc 2015, vi, 494–523.
The benzo[b]quinolizinium ion as a water-soluble platform for the fluorimetric detection of biologically relevant analytes
Open access: http://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/2015/

B. Aydıner, E. Yalçın, H. Ihmels, L. Arslan, L. Açık, Z. Seferoğlu, J. Photochem. Photobiol. A: Chem. 2015, 310, 113–121.
Arylstyrylimidazo[1,2-a]pyridine-based donor–acceptor acidochromic fluorophores: Synthesis, photophysical, thermal and biological properties.

D. V. Berdnikova, O. A. Fedorova, E. A. Tulyakova, H. Li, S. Kölsch, H. Ihmels,* Photochem. Photobiol. 2015, 91, 723–731.
Interaction of crown ether-annelated styryl dyes with double-stranded DNA

D. V. Berdnikova, T. Paululat, T. M. Aliyeu, Y. V. Fedorov, O. A. Fedorova, H. Ihmels, Chem. Commun. 2015, 51, 4906–4909.
DNA-Ligand Interactions Gained and Lost: Light-induced Ligand Redistribution in a Supramolecular Cascade

Z. Seferoğlu, H. Ihmels, E. Şahin, Dyes Pigm. 2015, 113, 465–473.
Synthesis and photophysical properties of fluorescent arylstyrylimidazo[1,2-a]pyridine-based donor-acceptor chromophores

D. V. Berdnikova, H. Ihmels, H. Schönherr, M. Steuber, D. Wesner, Org. Biomol. Chem. 2015, 13, 3766–3770.
Photoinduced Formation of Stable Ag-Nanoparticles from a Ternary Ligand-DNA-Ag+ Complex


2014

D. Dzubiel, H. Ihmels, M. M. A. Mahmoud, L. Thomas, Beilstein J. Org. Chem. 2014, 10, 2963–2974.
A comparative study of the interactions of cationic hetarenes with quadruplex-DNA forming oligonucleotide sequences of the insulin-linked polymorphic
region (ILPR)


R. Bortolozzi, S. von Gradowski, H. Ihmels, K. Schäfer, G. Viola, Chem. Commun. 2014, 50, 8242–8245.
Selective Ratiometric Detection of H2O2 in Water and in Living Cells with Boronobenzo[b]quinolizinium Derivatives

K. Benner, A. Bergen, H. Ihmels, P. M. Pithan, Chem. Eur. J. 2014, 20, 9883–9887.
Selective stabilization of abasic site-containing DNA by insertion of sterically demanding biaryl ligands

S. Yalcin, L. Thomas, N. Seferoglu, H. Ihmels, Y. Dede, J. Org. Chem. 2014, 79, 3799–3808.
One Proton, Two Effects – Switching-off the Charge Transfer and Closing the S1–T1 ISC Channel in Excited States of Quinolizinium Derivatives: A Theoretical Study

K. Benner, H. Ihmels, S. Kölsch, P. M. Pithan, Org. Biomol. Chem., 2014, 12, 1725–1734.
Targeting abasic site-containing DNA with annelated quinolizinium derivatives: The influence of size, shape and substituents

H. Ihmels, J. Liu, Z. Phys. Chem. 2014, 228, 229–242.
Stereoselective Di-π-Methane Rearrangement of a BINOL-Substituted Dibenzobarrelene Derivative


2013

H. Ihmels, J. Mattay, F. May, L. Thomas, Org. Biomol. Chem. 2013, 11, 51845188.
Photoswitchable DNA-binding properties of a photochromic spirooxazine derivative

R. Bortolozzi, H. Ihmels, L. Thomas, M. Tian, G. Viola,* Chem. Eur. J. 2013, 19, 8736–8741.
9-(4-Dimethylaminophenyl)benzo[b]quinolizinium: A near-infrared fluorophore for the multicolor analysis of proteins and nucleic acids in living cells


H. Ihmels, L. Thomas, Org. Biomol. Chem. 2013, 11, 480–487.
Light up G-quadruplex DNA with a [2.2.2]heptamethinecyanine dye


2012

A. Bergen, C. Bohne, D. Fuentealba, H. Ihmels, J. W. Bats, H.-J. Deiseroth, E. Neumann, Photochem. Photobiol. Sci. 2012, 11,1914–1921.
Studies of the Solvatochromic Emission Properties of N-Aroylurea Derivatives II: Influence of Hydrogen-Bonding Interactions

R. C. White, B. E. Arney, Jr., H. Ihmels, Beilstein J. Org. Chem. 2012, 8, 1208–1212.
Photoreactions of Cyclic Sulphite Esters: Evidence for Diradical Intermediates

K. Jäger, J. W. Bats, H. Ihmels, A. Granzhan, S. Uebach, B. O. Patrick, Chem. Eur. J. 2012, 18, 10903–10915.
Polycyclic Azoniahetarenes: Assessing the Binding Parameters of Complexes between Unsubstituted Ligands and G-Quadruplex DNA

D. Berdnikova, O. Fedorova, E. Gulakova, H. Ihmels, Chem. Commun. 2012, 48, 4603–4605.
Photoinduced in situ generation of a DNA-binding benzothiazoloquinolinium derivative

M. Tian, H. Ihmels, S. Ye, Org. Biomol. Chem. 2012, 10, 3010–3018.
Fluorimetric detection of Mg2+ and DNA with 9-(alkoxyphenyl)benzo[b]quinolizinium derivatives

A. Bergen, C. Bohne, D. Fuentealba,H. Ihmels, T. C. S. Pace, M. Waidelich, C. Yihwa, J. W. Bats, Photochem. Photobiol. Sci. 2012, 11, 752–767.
Studies of the Solvatochromic Emission Properties of N-Aroylurea Derivatives I: Influence of the Substitution Pattern


2011

K. Faulhaber, A. Granzhan, H. Ihmels, D. Otto, L. Thomas, S. Wells, Photochem. Photobiol. Sci. 2011, 10, 1535–1545.
Studies of the fluorescence light-up effect of amino-substituted benzo[b]quinolizinium derivatives in the presence of biomacromolecules

H. Ihmels in Science of Synthesis, Volume 15: Six-Membered Hetarenes with One Nitrogen or Phosphorus Atom, (Ed.: J. Thomas), Georg Thieme Verlag, Stuttgart, 2011, 75–91. Quinolizinium Salts and Benzo Analogues (Supplementary Update 2010)

S. V. Paramonov, V. Lokshin, H. Ihmels, O. A. Fedorova, Photochem. Photobiol. Sci. 2011,10, 1279–1282.
Influence of DNA-binding on the photochromic equilibrium of a chromene derivative

M. Tian, H. Ihmels, Eur. J. Org. Chem. 2011, 4145–4153.
Selective Colorimetric Detection of Hg2+ and Mg2+ with Crown Ether-Substituted N-Aryl-9-Aminobenzo[b]quinolizinium Derivatives

H. Ihmels, J. Luo, Beilstein J. Org. Chem. 2011, 7, 278–289.
Effects of Anion Complexation on the Photoreactivity of Bisureido- and Bisthioureido-Substituted Dibenzobarrelene Derivatives

H. Ihmels, J. Luo, Beilstein J. Org. Chem. 2011, 7, 119–126.
Synthesis of Cationic Dibenzosemibullvalene-Based Phase-Transfer Catalyst by Di-π-Methane Rearrangements of Pyrrolinium-Annelated Dibenzobarrelene Derivatives

H. Ihmels, L. Thomas, Materials Science of DNA Chemistry,(Ed.: J.-I. Jin), CRC Press, Boca Raton, 2011, 49.
Intercalation of Organic Ligands as a Tool to Modify the Properties of DNA


2010

H. Ihmels, L. Thomas in Materials Science of DNA Chemistry, (Ed.: J.-I. Jin), CRC Press, Boca Raton, 2011, 49–75.
Intercalation of Organic Ligands as a Tool to Modify the Properties of DNA

R. I. Zubatyuk, O. V. Shishkin, H. Ihmels, I. A. Lebedyeva, M. V. Povstyanoy, Acta Cryst. 2010, E66, o1762–o1763.
Ethyl 1,6-dimethyl-2-oxo-4-(quinolin-4-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

M. Tian, H. Ihmels, K. Benner, Chem. Commun. 2010, 46, 5719–5721.
Selective Detection of Hg2+ in the Microenvironment of Double-Stranded DNA with an Intercalator Crown-Ether Conjugate

M. Tian, H. Ihmels, E. Brötz, Dalton Trans., 2010, 39, 8195–8202.
Hydrolytic DNA Cleavage by the Cu(II) complex of the DNA-intercalating 9-bis(pyridin-2-ylmethyl)aminobenzo[b]quinolizinium


2009

M. Tian, H. Ihmels, Synthesis 2009, 4226–4234.
Synthesis of Fluorescent 9-Aryl-Substituted Benzo[b]quinolizinium Derivatives

H. Zhuang, V. V. S. S. Srikanth, X. Jiang, J. Luo, H. Ihmels, I. Aronov, B. W. Wenclawiak, M. Adlung, C. Wickleder, Appl. Phys. Lett. 2009, 95, 143703(1–3).
Allylamine-mediated DNA attachment to polycrystalline diamond surface

M. Tian, H. Ihmels, Chem. Commun. 2009, 3175–3177.
Selective Ratiometric Detection of Mercury(II) Ions in Water with an Acridizinium-Based Fluorescent Probe

J. Luo, H. Ihmels, H.-J. Deiseroth, M. Schlosser, Can. J. Chem. 2009, 87, 619–626.
Controlling the Regioselectivity of the Di-p-Methane Rearrangements of 1,2-Naphtho-annelated Barrelene Derivatives – Solution versus Solid-State Photochemistry

H. Ihmels, K. Schäfer, Photochem. Photobiol. Sci. 2009, 8, 309–311.
Excited-State Acidity of the 8-Hydroxyacridizinium Ion - A Water-Soluble Photoacid

A. Granzhan, H. Ihmels, K. Jäger, Chem. Comm. 2009, 1249–1251.
Diazonia- and Tetraazoniapolycyclic Cations as Motif for Quadruplex-DNA Ligands


2008

S. Basili, G. Basso, A. Faccio, A. Granzhan, H. Ihmels,* S. Moro, G. Viola,* ChemMedChem 2008, 3, 1671–1676.
Diazoniapolycyclic Ions Inhibit Activity of Topoisomerase I and Growth of Certain Tumor Cell Lines

H. Ihmels, J. Luo, J. Photochem. Photobiol. A: Chem. 2008, 200, 3–9.
The Reversible [4+4] Photocycloaddition of Acridizinium Derivatives

A. Bergen, A. Granzhan, H. Ihmels, Photochem. Photobiol. Sci. 2008, 7, 405–407.
Water-soluble, pH-sensitive fluorescent probes on the basis of acridizinium ions

T. Delatour, A. Mally, J. Richoz, S. Özden, W. Dekant, H. Ihmels, D. Otto, D. Gasparutto, M. Marin-Kuan, B. Schilter, C. Cavin, Mol. Nutr. Food Res. 2008, 52, 472–482.
Absence of 2’-deoxyguanosine-carbon 8-bound ochratoxin A adduct in rat kidney DNA monitored by isotope dilution LC-MS/MS

H.-J. Deiseroth, A. Granzhan, H. Ihmels, M. Schlosser, M. Tian, Org. Lett. 2008, 5, 757–760.
Synthesis of 6-Amino-3,4-Dihydroisoquinolinium Derivatives by Ring-Opening Reactions of Acridizinium Ions


2007

S. Basili, A. Bergen, F. Dall'Acqua, A. Faccio, A. Granzhan, H. Ihmels, S. Moro, G. Viola, Biochemistry 2007, 46, 12721–12736.
Relationship between the Structure and the DNA-Binding Properties of Diazoniapolycyclic Duplex- and Triplex-DNA Binders: Efficiency, Selectivity and Binding Mode

K. Benner, A. Granzhan, H. Ihmels, G. Viola, Eur. J. Org. Chem. 2007, 4721–4730.
Targeting Abasic Sites in DNA by Aminoalkyl-Substituted Acridizinium Carboxamides and Acridizinium–Adenine Conjugates

R. Wang, L. Yuan, H. Ihmels, D. H. Macartney, Chem. Eur. J. 2007, 13, 6468–6473.
Cucurbit[8]uril/Cucurbit[7]uril Controlled Off/On Fluorescence of the Acridizinium and 9-Aminoacridizinium Cations in Aqueous Solution

A. Granzhan, H. Ihmels, G. Viola, J. Am. Chem. Soc. 2007, 129, 1254–1267.
9-Donor-Substituted Acridizinium Salts: Versatile Environment-Sensitive Fluorophores for the Detection of Biomacromolecules

M. Albrecht, C. Bohne, A. Granzhan, H. Ihmels,* T. C. S. Pace, A. Schnurpfeil, M. Waidelich, C. Yihwa, J. Phys. Chem. A 2007, 111, 1036–1044.
Dual Emission of 2-Methoxyanthracene Derivatives

A. Granzhan, H. Ihmels, ARKIVOC 2007, viii, 136–149.
Synthesis of 9-amino- and 9-sulfanyl-substituted benzo[b]quinolizinium derivatives
Open Access: http://www.arkat-usa.org/home.aspx?VIEW=MANUSCRIPT&MSID=2128


2006

H. Ihmels, D. Otto, A. Faccio, G. Viola, J. Org. Chem. 2006, 71, 8401–8411.
Comparative Studies on the DNA-binding Properties of Linear and Angular Dibenzoquinolizinium Ions

H. Ihmels, A. Salbach, Photochem. Photobiol. 2006, 82, 1572–1576.
Unexpected and efficient photoinduced DNA damage by coralyne

K. Faulhaber, A. Granzhan, H. Ihmels, G. Viola, Pure Appl. Chem. 2006, 78, 2325–2331.
Detection of biomacromolecules with fluorescent light-up probes

A. Granzhan, J. W. Bats, H. Ihmels, Synthesis 2006, 1549–1555.
Synthesis and Spectroscopic Properties of 4a,14a-Diazonia­anthra[1,2-a]­anthracene and 13a,16a-Diazoniahexaphene Derived from 2,7-Dimethyl­naphthalene

A. Granzhan, H. Ihmels, ChemBioChem. 2006, 7, 1031–1033.
Selective Stabilization of Triple-Helical DNA by Diazoniapolycyclic Intercalators


2005

E. N. Andryukhina, O. A. Fedorova, Y. V. Fedorov, M. A. Panfilov, H. Ihmels, M. V. Alfimov, S. P. Gromova, Russ. Chem. Bull., Int. Ed. 2005, 54, 1328–1330.
Electrocyclic reaction of crown-containing 2-styrylbenzothiazoles

C. Bohne, H. Ihmels, M. Waidelich, C. Yihwa, J. Am. Chem. Soc. 2005, 127, 17158–17159.
The N-Acylureido Functionality as Acceptor Substituent in Solvatochromic Fluorescence Probes - Detection of Carboxylic Acids, Alcohols and Fluoride Ions

A. Granzhan, H. Ihmels, Org. Lett. 2005, 7, 5119–5122.
N-Aryl-9-amino-substituted Acridizinium Derivatives as Fluorescent “Light-up” Probes for DNA and Protein Detection

A. Granzhan, H. Ihmels, K. Mikhlina, H.-J. Deiseroth, H. Mikus, Eur. J. Org. Chem. 2005, 4098–4108.
Synthesis of Substituted Diazoniapentaphene Salts by an Unexpected Rearrangement-Cyclodehydration Sequence

H. Ihmels, K. Faulhaber, D. Vedaldi, F. Dall'Acqua, G. Viola, Photochem. Photobiol. 2005, 81, 1107–1115.
Intercalation of organic dye molecules into double-stranded DNA Part 2: The annelated quinolizinium ion as a structural motif in DNA intercalators

H. Ihmels, A. Meiswinkel, C. J. Mohrschladt, D. Otto, M. Waidelich, M. Towler, R. White, J. Org. Chem. 2005, 70, 3929–3938.
Anthryl-Substituted Heterocycles as Acid-Sensitive Fluorescence Probes

H. Ihmels, D. Otto, Top. Curr. Chem. 2005, 258, 161–204.
Intercalation of organic dye molecules into double-stranded DNA – General principles and recent developments

M. Benitez, G. Bringmann, M. Dreyer, H. Garcia,* H. Ihmels, M. Waidelich, K. Wissel, J. Org. Chem. 2005, 70, 2315–2321.
Design of a Chiral Mesoporous Silica and its Application as Catalyst in Stereoselective Di-π-Methane Rearrangement

C. Bohne, K. Faulhaber, B. Giese, A. Häfner, A. Hofmann, H. Ihmels, A.-K. Köhler, S. Perä, F. Schneider, M. A. L. Sheepwash, J. Am. Chem. Soc. 2005, 126, 76–85.
Studies on the mechanism of the photoinduced DNA damage in the presence of acridizinium salts - Involvement of singlet oxygen and an unusual source for hydroxyl radicals

H. Schaefer, K. Seibel, M. Walder, L. Schoeler, T. Pletzer, M. Waidelich, H. Ihmels, D. Ehrhardt, M. Boehm, in MEMS2005 Miami, Technical Digest, IEEE, Miami, FL, USA, 2005, 758-761.
Monolithic Integrated Optical Detection for Microfluidic Systems using Thin Film Photodiodes based on Amorphous Silicon


2004

H. Schäfer, K. Seibl, M. Walder, L. Schöler, T. Pletzer, M. Waidelich, H. Ihmels, M. Schmittel, D. Erhardt, M. Böhm* in Micro Total Analysis Systems 2004 – Proceedings of mTAS 2004 8th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Royal Society of Chemistry, Cambridge UK, 2004, 443–445.
A micro cytometer with monolithically integrated optical detectors based on amorphous silicon

H. Ihmels in Science of Synthesis, Volume 15: Six-Membered Hetarenes with One Nitrogen or Phosphorus Atom, (Ed.: D. Black), Georg Thieme Verlag, Stuttgart, 2004, 907–946.
Quinolizinium Salts and Benzo Analogues

G. Viola, H. Ihmels, H. Kraußer, D. Vedaldi, F. Dall’Acqua, ARKIVOC 2004, v, 219–230.
DNA-binding and DNA-photocleavaging properties of 12a,14a-diazoniapentaphene
Access: http://www.arkat-usa.org/ark/journal/2004/I05_Tortorella/VT-1085L/1085L.asp

A. Mally, H. Zepnik, P. Wanek, E. Eder, K. Dingley, H. Ihmels, W. Völkel, W. Dekant, Chem. Res. Toxicol. 2004, 17, 234–242.
Ochratoxin A: Lack of Formation of Covalent DNA Adducts

H. Ihmels, K. Faulhaber, G. Viola in Highlights in Bioorganic Chemistry: Methods and Applications, (Eds.: C. Schmuck, H. Wennemers), Wiley-VCH, Weinheim, 2004, 172–187.
Evaluation of the DNA-binding properties of cationic dyes by absorption and emission spectroscopyOpen


2003

H. Ihmels, S. Bosio, M. Bressanini, A. Schmitt, K. Wissel, D. Leusser, D. Stalke, Mol. Cryst. Liq. Cryst. 2003, 390, 105–112.
The Influence of the Substitution Pattern of Acridizinium Salts on the Regioselectivity of the Solid-State Photodimerization

H. Ihmels, K. Faulhaber, K. Wissel, G. Viola, D. Vedaldi, Org. Biomol. Chem. 2003, 1, 2999–3001.
6-Aminoacridizinium bromide: A fluorescence probe which lights up in AT-rich regions of DNA


2002

Z. Fei, N. Kocher, C. J. Mohrschladt, H. Ihmels, D. Stalke, Angew. Chem., 2003, 115, 807–811.
Single Crystals of the disubstituted anthracene {(Ph2P=S)2C14H8} selectively sensing toluene by solid-state fluorescence emission

E. Sliwinska, J. Sworakowski, H. Ihmels, J. Photochem. Photobiol. A: Chem. 2002, 151, 81–88.
DSC technique in studies of solid state reactions in photochromic materials

G. Viola, M. Bressanini, N. Gabellini, D. Vedaldi, F. Dall‘Acqua, H. Ihmels, Photochem. Photobiol. Sci. 2002, 1, 882–889.
Naphthoquinolizinium derivatives as novel platform for DNA-binding and DNA-photodamaging chromophores

H. Ihmels, C. J. Mohrschladt, A. Schmitt, M. Bressanini, D. Leusser, D. Stalke, Eur. J. Org. Chem. 2002, 2624–2632.
Photochromism and Highly Regioselective Solid-State Photodimerization of Naphthoquinolizinium Salts

H. Ihmels, C. J. Mohrschladt, A. Schmitt, M. Bressanini, D. Leusser, D. Stalke, Eur. J. Org. Chem. 2002, 2624–2632.
Photochromism and Highly Regioselective Solid-State Photodimerization of Naphthoquinolizinium Salts

G. Viola, F. Dall'Acqua, N. Gabellini, S. Moro, D. Vedaldi, H. Ihmels, ChemBioChem 2002, 3, 550–558.
Indolo[2,3-b]-Quinolizinium Bromide: An Efficient Intercalator with DNA-Photodamaging Properties

2001

H. Ihmels, D. Leusser, M. Pfeiffer, D. Stalke, Mol. Cryst. Liq. Cryst. 2001, 356, 433–441.
Solid-State Photodimerization of 9-Substituted Acridizinium Salts - Selectivity by Directional π Stacking

G. Bringmann, M. Münchbach, D. Feineis, K. Faulhaber, H. Ihmels, Neuroscience Lett., 2001, 304, 41–44.
Studies on DNA Single-Stranded Scissions by 'TaClo' (1-trichlormethyl-1,2,3,4-tetrahydro-b-carboline)

H. Ihmels, K. Faulhaber, K. Wissel, G. Bringmann, K. Messer, G. Viola, D. Vedaldi, Eur. J. Org. Chem. 2001, 1157–1161.
Synthesis and Investigation of the DNA-Binding and DNA-Photodamaging Properties of Indolo-[2,3-b]-Quinolizinium Bromide

H. Ihmels, C. J. Mohrschladt, J. W. Grimme, H. Quast, Synthesis, 2001, 1175–1180.
Investigation of the Regioselectivity of the Di-p-Methane-Rearrangement of 1,4-Dialkoxy-9,10-bis(methoxycarbonyl)dibenzobarrelenes in Solution and in the Solid State

H. Ihmels, K. Faulhaber, C. Sturm, G. Bringmann, K. Messer, N. Gabellini, D. Vedaldi, G. Viola, Photochem. Photobiol. 2001, 74, 505–511.
Acridizinium Salts as a Novel Class of DNA-Binding and Site-Selective DNA-Photodamaging Chromophores

J. Belzner, U. Dehnert, H. Ihmels, Tetrahedron 2001, 57, 511–517.
Reactions of Cyclotrisilanes with Styrene Derivatives and Diarylacetylenes – Evidence for Nucleophilic Silylenes


2000

H. Ihmels, A. Meiswinkel, C. J. Mohrschladt, Org. Lett. 2000, 2, 2865–2867.
Novel Fluorescence Probes Based on 2,6-Donor-Acceptor-Substituted Anthracene Derivatives

H. Ihmels, D. Leusser, M. Pfeiffer, D. Stalke, Tetrahedron 2000, 56, 6867–6875.
Solid-State Photolysis of Anthracene-Linked Ammonium Salts: The Search for Topochemical Anthracene Photodimerizations

H. Ihmels, K. Faulhaber, B. Engels, C. Lennartz, Chem. Eur. J. 2000, 6, 2854–2864.
New Dyes Based on Amino-Substituted Acridizinium Salts – Synthesis and Exceptional Photochemical Properties

1999

H. Ihmels, D. Leusser, M. Pfeiffer, D. Stalke, J. Org. Chem. 1999, 64, 5715–5718.
Regioselective Photodimerization of 9-Substituted Acridizinium Salts in the Solid State

H. Ihmels, Eur. J. Org. Chem. 1999, 1595-1600.
Synthesis, Fluorescence Properties and Head-to-Tail Regioselectivity in the Photo­dimerization of a Donor-Acceptor-Substituted AnthraceneJ. Belzner, H.

H. Ihmels, J. R. Scheffer, Tetrahedron 1999, 55, 885–907.
The Norrish/Yang Reaction in the Crystalline State: Toward a Better Understanding of the Geometric Requirements for d-Hydrogen-Atom Abstraction

H. Ihmels, B. O. Patrick, J. R. Scheffer, J. Trotter, Tetrahedron 1999, 55, 2170–2182.
11,12-Bis(diethylaminomethyl)-9,10-dihydro-9,10-ethenoanthracene: A Probe for the Heavy-Atom Effect in Solid-State Photoreactions

R. C. White, T. Selvam, H. Ihmels, W. Adam, J. Photochem. Photobiol. A: Chem. 1999, 122, 7–10.
Photolysis of N-phenylhydroxylamine: A Novel Photochemical Disproportionation Reaction in N–O Bond Cleavage Assisted by Hydrogen Bonding

Ihmels, Adv. Organomet. Chem. 1999, 43, 1–42.
Silylenes Stabilized by Coordination


1998

J. Belzner, U. Dehnert, H. Ihmels, M. Hübner, P. Müller, I. Usón, Chem. Eur. J. 1998, 4, 852–863.
New Dichlorosilanes, Cyclotrisilanes, and Silcyclopropanes as Precursors of Intramolecularly Coordinated Silylenes

H. Ihmels, Tetrahedron Lett. 1998, 39, 8641–8642.
Synthesis and Enhanced Regioselectivity in the Photodimerization of 9-Aminoacridizinium Perchlorate

 


1997

J. R. Scheffer, H. Ihmels, Liebigs Ann./Recueil 1997, 1925–1929.
Photochemistry of 11,12-Bis(aminomethyl)-9,10-dihydro-9,10-ethenoanthracene in Solution and in the Solid State


1996

J. Belzner, H. Ihmels in Synthetic Methods of Organometallic and Inorganic Chemistry, (Ed.: W. A. Herrmann), Georg Thieme Verlag, Stuttgart, 1996, 185–186.
Hexakis[2-(dimethylaminomethyl)phenyl]cyclotrisilane

J. Belzner, H. Ihmels in Organosilicon Chemistry II, (Eds.: N. Auner, J. Weiss), VCH, Weinheim, 1996, 75–79.
Cyclotrisilane and Silacyclopropane - An Equilibrium

J. Belzner, H. Ihmels, L. Pauletto, J. Org. Chem. 1996, 61, 3315–3319.
Reactions of a Silanediyl with Carbon–Oxygen and Carbon–Nitrogen Double Bonds

J. Belzner, H. Ihmels, B. O. Kneisel, R. Herbst-Irmer, Chem. Ber. 1996, 129, 125–130
Chalcogen Transfer to Bis[2-(dimethylaminomethyl)phenyl]silanediyl by Isocyanates and Isothiocyanates

1995

J. Belzner, H. Ihmels, M. Noltemeyer, Tetrahedron Lett. 1995, 96, 8187–8190.
Reactivity of a Silanediyl towards Nitriles – The Role of Azasilacyclopropenes as Intermediates

J. Belzner, H. Ihmels, B. O. Gould, B. O. Kneisel, R. Herbst-Irmer, Organometallics 1995, 14, 305–311.
Reactions of a Cyclotrisilane with Olefins and Dienes: Evidence for an Equilibrium between Silylenes and a Cyclotrisilane

1994

J. Belzner, N. Detomi, H. Ihmels, M. Noltemeyer, Angew. Chem. 1994, 106, 1949–1950
Structures of 2(Me2NCH2)-C6H4-Substituted Oligosilanes

J. Belzner, H. Ihmels, B. O. Kneisel, R. Herbst-Irmer, J. Chem. Soc., Chem. Commun. 1994, 1989–1990.
Reactions of a Cyclotrisilane with Alkynes: Synthesis and First Crystal Structure of 1,2‑Disilacyclobut-9-enes

1993


1992

J. Belzner, H. Ihmels, Tetrahedron Lett. 1993, 34, 6541–6544.
A Novel Route to Stable Silacyclopropenes - First Synthesis of Silacyclopropenes Bearing Vinylic Hydrogen


1991

H. Ihmels, M. Maggini, M. Prato, G. Scorrano, Tetrahedron Lett. 1991, 32, 6215–6218.
Oxidation of Diazo Compounds by Dimethyl Dioxirane: An Extremely Mild an Efficient Method for the Preparation of Labile a-Oxo-Aldehydes

Book reviews, Editorials,etc.

H. Ihmels, Arkivoc, 2007, viii, 1–6.
Prof. Waldemar Adam

A. Griesbeck, H. Ihmels, K. Licha, T. Mielke, M. Senge, B. Strehmel, D. Wöll, Nachr. Chem. 2014, 62, 612–616.
Licht für Medizin und Diagnostik~

H. Ihmels, GDCh-Wochenschau from 29.11.2015 (www.aktuelle-wochenschau.de/main-navi/aktuelle-wochenschau-2015.html)
Gezielte lichtgesteuerte Assoziation und Dissoziation von photochromen Liganden und DNA

H. Ihmels, T. Linker, A. Trofimov, J. Phys. Org. Chem. 2017, 30, e3745.
Editorial (Special Issue: Special issue dedicated to Waldemar Adam on the occasion of his 80th birthday)

H. Ihmels, EPA Newsletter 2018, 57.
Conference report: 26th Lecture Conference on Photochemistry, Garching/Munich