Dr. Nowsheen Goonoo
Phone: +49 (0)271 740 2915
Bone tissue engineering (TE) aims to eliminate many of the pitfalls associated with current bone graft transplantation processes, including donor site morbidity, limited supplies of bone grafts and risk of disease transmission. Material properties of scaffolds, in particular their chemical nature, mechanical performance, topographical cues and degradation rate are known to affect scaffold performance. The main aim of this research project is to rationalize the biological performance of synthetic/natural polymer blend scaffolds by establishing the relationship with their physico-chemical and mechanical properties. In particular, miscibility characteristics and phase separation mechanisms will be investigated and their impact on physico-chemical properties assessed. Moreover, the in vitro biocompatibility of the blends will be tested using a range of cell lines ranging from fibroblasts to osteoblasts.